Research progress of periodontal tissue regeneration by combined biomaterials of dental derived mesenchymal stem cells
10.13591/j.cnki.kqyx.2023.03.014
- VernacularTitle:联合生物材料的牙源性间充质干细胞进行牙周组织再生的研究进展
- Author:
Yiyu WANG
1
;
Jiaping HUANG
;
Peihui DING
;
Yan DONG
Author Information
1. Department of Prosthodontics, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310009, China
- Publication Type:Review
- Keywords:
mesenchymal stem cell;
biomaterial;
periodontal tissue regeneration;
tissue engineering
- From:
STOMATOLOGY
2023;43(3):261-266
- CountryChina
- Language:Chinese
-
Abstract:
The ultimate treatment goal of periodontitis is the structural and functional regeneration of periodontium. However, existing methods for periodontal regeneration have difficulties in regenerating the hierarchical structure. Therefore, stem cell-based tissue engineering has attracted more and more attention for its advantages of self-renewal and multi-lineage differentiation potential. This review summarized the progress of research on periodontal tissue regeneration by combined biomaterials of dental-derived stem cells. It is pointed out that the application of autologous stem cell transplantation is limited by the donor source, and the subsequent research should focus on the development of multi-phase scaffold materials and the attempt to establish a stem cell bank.
