Application of small molecular compounds in promoting the repair of dentin-pulp complex injury
10.13591/j.cnki.kqyx.2023.03.013
- VernacularTitle:小分子化合物促进牙髓牙本质复合体损伤修复的研究进展
- Author:
Jiaojiao SHAO
1
;
Qi ZHANG
Author Information
1. Department of Dentistry and Endodontics,Stomatological Hospital and Dental School of Tongji University, Shanghai Engineering Research Center of Tooth Restoration and Regeneration, Shanghai 200072, China
- Publication Type:Review
- Keywords:
dentin-pulp complex;
tissue repair;
small molecule compound
- From:
STOMATOLOGY
2023;43(3):256-261
- CountryChina
- Language:Chinese
-
Abstract:
Dental caries, trauma, and iatrogenic stimulation can cause damage to the dentin-pulp complex. Preserving the viable pulp and promoting damage repair of the dentin-pulp complex is of great clinical significance at present. In recent years, studies have found that various small molecular compounds can regulate inflammation, promote the migration, proliferation, and differentiation of dental pulp stem cells, promote blood vessel, nerve regeneration and other biological processes by regulating key intracellular signaling pathways and metabolic pathways, and could thereby promote damage repair of the dentin-pulp complex. The objective of this paper is to review recent research on various small molecular compounds used in promoting the repair of dentin-pulp complex.
