Correlation between Toxoplasma infection and occurrence of children with cerebral palsy
- VernacularTitle:弓形虫感染致小儿脑性瘫痪的危险性分析
- Author:
Rui-hua LI
;
Xiao-wei FENG
;
Ying HUANG
- Publication Type:Journal Article
- Keywords:
Toxoplasma, cerebral palsy, occurrence, children
- From:
Chinese Journal of Rehabilitation Theory and Practice
2004;10(9):553-553
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate whether the Toxoplasma infection is the risk factor of occurrence of children cerebral palsy.Methods236 children with cerebral palsy and 428 normal children were included. Children were laminated to 4 groups by age:-3 months,-6 months,-9 months,-12 months. Final diagnosis was made by one or more finding following: plasma Toxoplasma DNA(TOX-DNA), plasma Toxoplasma circulating antigen(TOX-CAG), plasma Toxoplasma IgM(TOX-IgM), exclusion other congenital infected diseases.ResultsThe OR and 95%CI were 10.13,3.74-27.42 in -3 months,7.71,2.45-24.28 in -6 months,8.84,1.85-42.31 in-9 months(P<0.01 respectively), and 4.30, 0.83-22.28(P>0.05)in -12 months. ConclusionThere is correlation between the Toxoplasma infection and the children cerebral palsy; the earlier Toxoplasma infection, the greater the risk of cerebral palsy. Congenital Toxoplasma infection may be one of important factors in children cerebral palsy.
