Affecting Factors of Outcome of CC/hMG Ovarian Stimulation and Intrauterine Insemination.
- Author:
Yun Seok YANG
1
;
Jang Ok PARK
;
Kwan Young OH
;
Byung Kwan LEE
;
Joon Sook PARK
;
Jin Yong LEE
Author Information
1. Department of Obstetrics and Gynecology, Eulji University School of Medicine, Daejeon, Korea.
- Publication Type:Original Article
- Keywords:
Infertility;
CC/hMG ovarian stimulation;
IUI;
Pregnancy
- MeSH:
Diagnosis;
Endometrium;
Family Characteristics;
Female;
Humans;
Infertility;
Insemination*;
Logistic Models;
Ovulation Induction*;
Patient Selection;
Pregnancy;
Semen Analysis;
Sperm Count
- From:Korean Journal of Obstetrics and Gynecology
2004;47(7):1376-1384
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE: We have attempted to identify prognostic factors regarding CC/hMG ovarian stimulation and IUI in infertility and to seek factors valuable in planning infertility treatment and predicting the success rate of IUI therapy in individual couples. METHODS: The variables selected for initial analysis were female age, duration of infertility, type and diagnosis of infertility, number of pre-ovulatory follicles (>or=16 mm, >or=18 mm follicles), thickness of the endometrium, number of the treatment cycles, result of semen analysis, ovarian stimulation protocol, number of IUI. A logistic regression method was used to identify significant variables that contribute to the success of CC/hMG/IUI treatment. RESULTS: Logistic regression analysis revealed four predictive variables as regards pregnancy: duration of infertility (p=0.011), infertility etiology (p=0.049), number of IUI (p=0.004), method of ovarian stimulation (p=0.042). A cause of infertility, especially ovarian dysfunction other than tubal factor, a shorter duration of infertility (<6 years) and CC/hMG minimal ovarian stimulation protocol with double IUI resulted in better treatment success in CC/hMG with IUI cycles. CONCLUSION: We concluded that careful patient selection criteria coupled with successful ovarian stimulation and increased sperm count in female reproductive tract is the model for CC/hMG/IUI sucess.
