Successful Pregnancy after Paclitaxel-Cisplatin Chemotherapy in Invasive Squamous Cell Carcinoma of Cervix During Pregnancy: A Case Report and Review of the Literature.
- Author:
Seung Youn YU
1
;
So Ra RYU
;
Seung Hee CHA
;
Jung Yeol HAN
;
Jin Hoon JUNG
Author Information
1. Department of Obstetrics and Gynecology, Samsung Cheil Hospital and Women's Healthcare Center, Sungkyunkwan University, School of Medicine, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Paclitaxel;
Cisplatin;
Pregnancy
- MeSH:
Carcinoma, Squamous Cell*;
Cervix Uteri*;
Cesarean Section;
Cisplatin;
Drug Therapy*;
Female;
Gestational Age;
Growth and Development;
Humans;
Infant;
Lymph Node Excision;
Paclitaxel;
Pregnancy*;
Radiotherapy;
Recurrence;
Uterine Cervical Neoplasms
- From:Korean Journal of Obstetrics and Gynecology
2004;47(7):1385-1388
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Paclitaxel-Cisplatin based chemotherapy in invasive squamous cell carcinoma of cervix during pregnancy has not been reported previously. A woman was diagnosed with stage II b invasive squamous cell carcinoma of cervix during pregnancy at 27 weeks gestational age. She was treated with two cycles of paclitaxel and cisplatin during pregnancy. At 36 weeks, she underwent a classical cesarean section and bilateral paraaortic lymphadenectomy. One additional cycles of chemotherapy and radiotherapy were given. She developed a recurrence within 6 months of surgery. The infant has normal growth and development at 4.3 months of age. This is the first reported case of paclitaxel-cisplatin use in cervical cancer during pregnancy.
