Association between air pollutants and digestive system cancers: a systematic review
10.3969/j.issn.1006-2483.2023.04.001
- VernacularTitle:空气污染物与消化系统癌症之间的关联：系统综述
- Author:
Cuihong YANG
1
;
Wentao GU
1
;
Yubing SHEN
1
;
Luwen ZHANG
1
;
Wangyue CHEN
1
;
Jingmei JIANG
1
Author Information
1. Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences / Department of Epidemiology and Health Statistics, College of Basic Medical Sciences , Beijing 100005 , China
- Publication Type:Journal Article
- Keywords:
Air pollutants;
Digestive system cancers;
Systematic review;
Meta-analysis
- From:
Journal of Public Health and Preventive Medicine
2023;34(4):1-6
- CountryChina
- Language:Chinese
-
Abstract:
Objective To understand the relationship between air pollutants and digestive system cancers, and to provide a reference for future research and prevention and control of digestive system cancer. Methods All relevant literature published in English between 1970-2022 was searched through the databases of PubMed, web of science and Embase, and meta-analysis was used to explore the effects of specific air pollutants on digestive system cancers. Results PM2.5 was able to increase the risk of incidence or mortality of total digestive cancers by 11% (1.05 to 1.17). For specific cancers, PM2.5 was only associated with an increased risk of liver cancer in this study, with a combined RR (95% CI) of 1.31 (1.19 to 1.46), while there was no statistically significant association with other specific digestive cancers ( P>0.05）. NO2 increased the risk of incidence or mortality of total digestive cancers by 3% (1.00 to 1.07). Conclusion For specific digestive system cancers, PM2.5 has the most pronounced effect on liver cancer. More evidence is needed to support the relationship between NO2 and cancer. Currently, it has been observed that NO2 has a negative effect on overall digestive cancers. This study provides insights for the prevention and control of digestive system cancer in countries and regions with high PM2.5 and NO2 concentrations.
