Research advances in the role of
10.3969/j.issn.1001-5256.2023.07.026
- VernacularTitle:粪肠球菌在酒精性肝病中的研究进展
- Author:
Boyuan GU
1
;
Shengyou XIAO
1
;
Chen LIU
1
;
Yonglang CHENG
1
;
Wenguang FU
1
,
2
Author Information
1. Department of General Surgery (Hepatopancreatobiliary Surgery), The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan 646000, China
2. Academician (Expert) Workstation of Sichuan Province, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan 646000, China
- Publication Type:Review
- Keywords:
Liver Diseases, Alcoholic;
Enterococcus faecalis;
Gastrointestinal Microbiome;
Intestinal Mucosa
- From:
Journal of Clinical Hepatology
2023;39(7):1696-1702
- CountryChina
- Language:Chinese
-
Abstract:
Alcoholic liver disease (ALD) is one of the most common chronic liver diseases worldwide and includes the different stages of steatosis, steatohepatitis, fibrosis, and liver cirrhosis. Enterococcus faecalis is a common bacterium for nosocomial infection and has a significant impact on the prognosis of patients with alcoholic hepatitis. This review mainly introduces the pathogenesis of ALD and the pathogenic mechanism of E. faecalis , summarizes the research advances in E. faecalis in ALD, and briefly describes the detection and treatment methods for E. faecalis infection in clinical practice. Since there is an extremely high mortality rate in ALD patients with lytic E. faecalis infection, an in-depth understanding of E. faecalis has become an important issue nowadays.