Research advances in natural killer cell-based immunotherapy in liver cancer
10.3969/j.issn.1001-5256.2023.06.034
- VernacularTitle:基于NK细胞的免疫治疗在肝癌中的研究进展
- Author:
Shiji CHENG
1
;
Tianrui KUANG
1
;
Keshuai DONG
1
;
Jia YU
1
Author Information
1. Department of Hepatobiliary Surgery, Renmin Hospital of Wuhan University, Wuhan 430060, China
- Publication Type:Review
- Keywords:
Liver Neoplasms;
Killer Cells;
Natural;
Immunotherapy
- From:
Journal of Clinical Hepatology
2023;39(6):1476-1481
- CountryChina
- Language:Chinese
-
Abstract:
Natural killer (NK) cells are important immune cells in the human body and are also the main lymphocytes in the liver. They are considered the first defense mechanism against tumor and have a significant impact on the development and progression of liver cancer. The characteristics of NK cells help them become a new choice for immunotherapy, and NK cell-based immunotherapy may succeed in the treatment of liver cancer. This article reviews the biological characteristics of NK cells, their role in the development and progression of liver cancer, and the research advances in related treatment.