Advances in the pathogenesis, diagnosis, and treatment of renal injury in liver cirrhosis
10.3969/j.issn.1001-5256.2023.06.032
- VernacularTitle:肝硬化肾损伤的发病机制与诊治进展
- Author:
Qingqing LIU
1
;
Jing YANG
1
;
Shaoshan HU
1
;
Pingju LI
1
;
Qiu JIN
1
;
Honglin MA
1
Author Information
1. Department of Gastroenterology, the Second Affiliated Hospital of Kunming Medical University, Kunming 650106, China
- Publication Type:Review
- Keywords:
Liver Cirrhosis;
Kidney Injury;
Diagnosis;
Therapeutics
- From:
Journal of Clinical Hepatology
2023;39(6):1461-1467
- CountryChina
- Language:Chinese
-
Abstract:
Patients with decompensated cirrhosis often have a reduction in renal function due to severe hepatic insufficiency which results in reduced inactivation of vasodilators, hemodynamic disorders, immune disorders, and infections, and without timely intervention, patients may gradually develop from early prerenal injury to late renal failure. Patients tend to have a low survival rate and great difficulties in treatment. With the gradual clarification of the classification and diagnostic criteria for kidney injury and the discovery of an increasing number of markers for kidney injury, early diagnosis and localization of kidney injury are of great importance for improving the prognosis of patients. This article analyzes the new advances in the pathogenesis, diagnostic criteria, and treatment of renal injury in cirrhotic patients in recent years, so as to provide help for the clinical diagnosis and treatment of cirrhotic patients with renal injury.