Rapid identification of the chemical compounds in the leaves of Solanum nigrum L. based on UHPLC-Q Exactive MS and molecular network technology
10.16438/j.0513-4870.2022-1162
- VernacularTitle:基于UHPLC-Q Exactive MS的分子网络技术快速分析龙葵叶物质成分
- Author:
Xian-long DONG
;
Lin-jiao YANG
;
Xue-mei QIN
;
Zhen-yu LI
- Publication Type:Research Article
- Keywords:
UHPLC-Q Exactive MS;
italic>Solanum nigrum L.;
GNPS molecular network;
steroid alkaloids;
steroid saponins;
flavonoids
- From:
Acta Pharmaceutica Sinica
2023;58(4):1003-1013
- CountryChina
- Language:Chinese
-
Abstract:
The whole herb of Solanum nigrum L. can be used as the herbal drug. In this study, UHPLC-Q Exactive high resolution mass combined with GNPS molecular network was used for the rapid characterization of the components in the leaves of S. nigrum L. A total of 157 compounds were identified, including 30 steroid alkaloids, 61 steroid saponins, 35 flavonoids, and 31 other compounds (amino acids and organic acids), by comparison with the data reported in the literature, and mass fragmentation characteristics analysis, as well as the correlation of known and unknown nodes in the GNPS molecular network. Compared with the fruits and stems, the leaves of S. nigrum L was rich in a variety of steroidal saponins, steroidal alkaloids, and flavonoids, and the results lay the foundation for the precise resources utilization of S. nigrum L.
