Inconsistency of Lesion Quantitative Assessment in 2D SUV and 3D SUV Quantification Techniques for [18F]-FDG PET/CT: A Phantom Study
- Author:
Muhammad Hafiz Hanafi
1
;
Noramaliza Mohd Noor
2
,
3
;
Muhammad Hishar Hassan
1
Author Information
- Publication Type:Other Types
- Keywords: Quantification, 18F-FDG, SUVmax, SUVavg, SUVmin, PET/CT
- From:Malaysian Journal of Medicine and Health Sciences 2021;17(No.2):289-293
- CountryMalaysia
- Language:English
- Abstract: This study was performed to assess the inconsistency of lesion quantification in standardised uptake value (SUV) [ 18F]-FDG between Ellipse (2-Dimensional) and Ellipsoid (3-Dimensional) quantification techniques by using PET/ CT image quality phantom. Reconstructed images of PET/CT ACR phantom was used to assess the quantification of SUV (SUVmax, SUVavg and SUVmin) on selected regions of interest. Statistical analysis of paired t-test was performed to compare the lesion quantification in SUV [18F]-FDG between 2D and 3D techniques. The quantification techniques were consistently similar of assessment between 2D SUVmax and 3D SUVmax at 12mm of ROI lesion with [(0.00 ± 0.02), t(29)=-0.48, p>0.05]. However, the rest of quantification techniques of 2D SUVmax, 3D SUVmax, 2D SUVavg, 3D SUVavg, 2D SUVmin and 3D SUVmin, results shown significant inconsistency since the p<0.05. This phantom study has proven that there were inconsistency of lesion quantitative assessment in 2D SUV and 3D SUV quantification techniques for [18F]-FDG PET/CT.
- Full text:11.2021my1052.pdf
