Research progress on acute lung injury/acute respiratory distress syndrome after liver transplantation
10.3969/j.issn.1674-7445.2023.04.004
- VernacularTitle:肝移植术后急性肺损伤/急性呼吸窘迫综合征的研究进展
- Author:
Wei QIU
1
;
Xuxiang XIA
;
Junpeng ZHANG
;
Xutao HU
Author Information
1. Liver Transplantation Center, the First Hospital of Jilin University, Changchun 130000, China
- Publication Type:Research Article
- Keywords:
Liver transplantation;
Acute lung injury;
Acute respiratory distress syndrome;
Ischemia-reperfusion injury;
Transfusion-related acute lung injury;
Inflammatory marker;
Lung-protective mechanical ventilation;
Extracorporeal membrane oxygenation
- From:
Organ Transplantation
2023;14(4):491-
- CountryChina
- Language:Chinese
-
Abstract:
Acute lung injury/acute respiratory distress syndrome (ALI/ARDS) is a common complication after liver transplantation, which could prolong the length of postoperative intensive care unit stay, affect clinical efficacy of liver transplantation and even lead to the death of recipients. ALI/ARDS has attracted extensive attention from liver transplant surgeons in clinical practice. ALI/ARDS after liver transplantation may be directly caused by pulmonary factors (such as mechanical ventilation-related lung injury, lung infection and aspiration, etc.) or indirectly induced by non-pulmonary factors (such as severe infection outside the lungs, blood transfusion and ischemia-reperfusion injury, etc.). In this article, the diagnostic criteria, incidence, mechanism, risk factors, laboratory and clinical diagnostic approaches and treatment of ALI/ARDS after liver transplantation were reviewed, aiming to deepen the understanding and cognition of ALI/ARDS during the perioperative period of liver transplantation and provide reference for the diagnosis and treatment of ALI/ARDS following liver transplantation.