Effect of arsenic trioxide on the expressions of human gastric cancer genes nm23 and P53
- VernacularTitle:三氧化二砷对人胃癌细胞株nm23、P53基因表达的影响
- Author:
Yahong DAI
;
Shumei LIU
;
Xin MENG
;
Tao LIANG
- Publication Type:Journal Article
- Keywords:
arsenic trioxide (As2O3), gene expression, cancer
- From:
Chinese Journal of Rehabilitation Theory and Practice
2005;11(8):626-627
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo detect the effect arsenic trioxide (As2O3) on the expressions of human gastric cancer genes nm23 and P53.MethodsThe expressions of proteins coded by nm23 and P53 were examined with immunohistochemistry method after treated by As2O3.ResultsThe expressions of proteins coded by nm23 and P53 decreased after treated by As2O3 (P<0.05).ConclusionAs2O3 can down-regulate the expressions of proteins coded by nm23 and P53.
