Change of testosterone and CD4+/CD8+ T cell in long-term mechanical ventilation patients with chronic obstructive pulmonary disease
- VernacularTitle:慢性阻塞性肺疾病长期机械通气患者血清睾酮、CD4+/CD8+ T细胞的变化
- Author:
Baojun SUN
;
Hongmei ZHAO
;
Lin ZOU
;
Changting LIU
;
Senyang YU
- Publication Type:Journal Article
- Keywords:
lung disease, chronic obstructive, elderly, mechanical ventilation, testosterone, CD4, CD8, T cell
- From:
Chinese Journal of Rehabilitation Theory and Practice
2005;11(7):568-569
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate the change of the level of testosterone and CD4+/CD8+ T cell in long-term mechanical ventilation patients with chronic obstructive pulmonary disease (COPD) and their correlation.MethodsThe level of testosterone, count of CD4+ and CD8+ T cell were measured in 42 COPD patients accepted long-term mechanical ventilation and other 34 stable COPD patients. The ratio of CD4+/CD8+ was calculated.The correlation between testosterone and CD4+/CD8+ was analyzed.ResultsCompared with the stabel COPD, there were significantly differences in the level of testosterone and the ratio of CD4+/CD8+ in long-term mechanical ventilation COPD group(P<0.05), but there was not relationship between them.ConclusionThe level of testosterone and the ratio of CD4+/CD8+ were significantly decreased in COPD patients with long-term mechanical ventilation. There is no correlation between the level of testosterone and the ratio of CD4+/CD8+.
