Change of thrombin antithrombin Ⅲ complex after acute brain infarction

VernacularTitle:急性脑梗死凝血酶抗凝血酶Ⅲ复合物的研究
Author: Jinli ZHANG ; Maolin HE
Publication Type:Journal Article
Keywords: acute brain infarction, thrombin antithrombin III complex, coagulative system
From: Chinese Journal of Rehabilitation Theory and Practice 2005;11(7):529-530
CountryChina
Language:Chinese
Abstract: ObjectiveTo determine the change of coagulation in acute brain infarction.MethodsBlood samples were taken intravenously from 57 patients with acute brain infarctions (within 24hr) and the thrombin time(TT), prothrombin time(PT), activated partial thromboplastin time(APTT), fibrinogen(FIB) levels were detected serially at the time of instant admission, 1st day ,3rd day and 7th day after routine therapy, including 21 patients whose thrombin antithrombin III complex(TAT) levels were detected at the same time.ResultsTAT levels were significant increased in acute brain infarctions, especially in acute progress stroke, but TT, PT, APTT were not significantly different before and after routine treatment. FIB levels were higher at 7th day than pre-treatment. ConclusionTAT levels can be served as a marker of progress stroke.