Effect of Yinaotongluo Capsule on diffuse weighting image and energy metabolism of ischemia-reperfused rats
- VernacularTitle:益脑通络胶囊对缺血再灌注大鼠弥散加权像及能量代谢的影响
- Author:
Meikui ZHANG
;
Maili LIU
;
Ling YIN
;
Xuesong WANG
;
Xu ZHANG
;
Yigen WU
;
Bin YAO
;
Xianglan JIN
- Publication Type:Journal Article
- Keywords:
Yinaotongluo Capsule, cerebral ischemia, ischemia and reperfusion, magnetic resonance diffusion-weighted imaging(DWI), 1H and magnetic resonance spectroscopy(MRS), rat
- From:
Chinese Journal of Rehabilitation Theory and Practice
2005;11(7):507-508
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo explore the effect of Yinaotongluo Capsule on diffuse weighting image and enenery metabolism of ischemia-reperfuing rat.MethodsMagnetic resonance diffusion-weighted imaging(DWI) and 1H and magnetic resonance spectroscopy(MRS) were performed in different brain regions in focal cerebral ischemic-reperfusion injury model rats. ResultsYinaotongluo Capsule could significantly reduce the area and the intensity of infarction of rats by DWI 3 h and 5 d after treatment compared with the model group.The result of 1H MRS examination demonstrated Lac peak was lower and NAA peak higher than that of the model group. ConclusionYinaotongluo Capsule can effectually improve enenery metabolism during cerebral ischemia and reperfuing, so that to reduce the neuronal dysfunction and death in infarcts at the late stage.
