Rat cerebral ischemia infarct model made by thread blocked directly in blood vessel
- VernacularTitle:血管内直接线栓闭塞法制备大鼠缺血性脑梗死模型
- Author:
Hong-song SONG
;
Dong-sheng FAN
;
Yin-hua WANG
- Publication Type:Journal Article
- Keywords:
rat, cerebral ischemia, animal model
- From:
Chinese Journal of Rehabilitation Theory and Practice
2004;10(4):245-246
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo standardize the process in making the model of acute regional cerebral ischemia in Sprague-Dawley rats, and to economize time and material.MethodsRegional cerebral ischemia rat's models were induced and modified according to Koizumi's method.ResultsThe time duration was controllable and the volume of cerebral infarct was determined by adverting the approaches such as the preparation of suture, anaesthesia of the animal, and the details of surgical operation.ConclusionThe acute regional cerebral ischemic model in rats made by Koizumi's method is stable and reliable, and is easy for the beginner to carry out under limited conditions.
