An atypical case of a 14-year-old Filipino female with non-classical congenital adrenal hyperplasia presenting with alopecia universalis
- Author:
Erwin John R. Aquino
1
;
Aira Monica R. Abella
1
;
Ma. Teresita G. Gabriel
1
Author Information
- Publication Type:Case Reports
- Keywords: Alopecia universalis
- MeSH: Minoxidil; Tretinoin
- From: Journal of the Philippine Dermatological Society 2022;31(2):41-43
- CountryPhilippines
- Language:English
-
Abstract:
Introduction:Non-classical congenital adrenal hyperplasia (CAH) represents a group of inherited, autosomal recessive disor-
ders that typically presents with androgenetic alopecia, but may present with alopecia universalis on rare occasions.
Case report:We report a case of a 14-year-old Filipino female with non-classical congenital adrenal hyperplasia presenting with alopecia universalis, treated with a combination of Tretinoin and Minoxidil solution, low dose prednisone and an oral supplement containing zinc gluconate, nicotinamide, superoxide dismutase, vitamin E and selenium, with noted gradual hair regrowth and improvement in Dermatology Life Quality Index (DLQI).
Conclusion:Alopecia universalis in a patient diagnosed with non-classical congenital adrenal hyperplasia is a rare and atypical manifestation, with no case reports available to describe its occurrence. Due to its rarity, there is no standard treatment for pa- tients with this condition. However, the combination of tretinoin and minoxidil solution, low dose prednisone and an oral supple- ment containing zinc gluconate, nicotinamide, superoxide dismutase, vitamin E and selenium shows promising results. - Full text:06_NOV 2022_AQUINO.pdf
