Experimental study on repairing bone defect with the compound of the allogeneic morselized bone
- VernacularTitle:复合同种异体颗粒骨修复兔桡骨缺损实验研究
- Author:
Zhipeng ZHANG
;
Bing YAN
;
Jinglong YAN
- Publication Type:Journal Article
- Keywords:
morselized bone, calcium phosphate cement, bone defect, vascularization
- From:
Chinese Journal of Rehabilitation Theory and Practice
2005;11(6):439-440
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo observe the effect of the compound of the allogeneic morselized bone and the calcium phosphate cement on repairing bone defect.MethodsThe rabbit models of bilateral radius bone defect were created. 40 rabbits were randomly divided into group A, group B and group C. Animals of the group A were implanted with the compound of the allogeneic morselized bone and the calcium phosphate cement, group B implanted with allogeneic morselized bone, and group C as blank control implanted nothing. The X-ray examination, histopatholgical examination, vascularization and biomechanics of bone defect were evaluated at 4 and 8 weeks after operation.ResultsThe repair of bone defect, quantity and rate of the new formation bone and biomechanics measurement of the group A were superior than the group B; while, no repair of bone defect was found in the group C.ConclusionThe implantation of the allogeneic morselized bone can repair bone defect, but the effect of implanting the compound of the allogeneic morselized bone and the calcium phosphate cement is better than the former.
