Relationship of lipids and lipoproteins with cardiac function in patients with coronary heart disease
- VernacularTitle:冠心病患者血脂和脂蛋白水平及与心功能的关系
- Author:
Zepeng LIN
;
Zhiwei ZHANG
;
Guanglin JIN
;
Changnong PENG
;
Weihua FANG
- Publication Type:Journal Article
- Keywords:
coronary heart disease (CHD), blood lipid, lipoproteins, left cardiac function
- From:
Chinese Journal of Rehabilitation Theory and Practice
2005;11(6):427-428
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate the correlation of lipids and lipoproteins with cardiac function in patients with coronary heart disease (CHD).MethodsParameters of blood pressure, serum lipids and lipoproteins, clinical features, radionuclide ventriculographic and coronary angiographic findings were analyzed retrospectively in 584 CHD patients treated with standard treatment.ResultsThe left cardiac dysfunction of CHD patients was correlative positively with age, systolic blood pressure (SBP), diastolic blood pressure (DBP), blood glucose, body mass index (BMI), smoking, total cholesterol(TC) and low density lipoprotein cholesterol(LDL-ch) significantly(P<0.001), not correlative with high density lipoprotein-cholesterol (HDL-ch). The left ventricular ejection fraction (LVEF) and left ventricular peak filling rate (LVPFR) were decreased along with the levels of TC and LDL-ch increased (P<0.05～0.01).ConclusionTC and LDL-ch are positively correlative with left cardiac dysfunction in CHD patients. In order to reduce cardiac damage of CHD associated with hyperlipoidemia, more attention should be paid to the amelioration of coronary arteriosclerosis and the reduction of serum lipids and lipoproteins.
