Effect of monosialo gangliosides-1 and Radix salviae miltiorrhizae on hyposemic ischemic encephalopathy

VernacularTitle:复方丹参和施捷因联合治疗新生儿缺氧缺血性脑病
Author: Wenying LI ; Wanhai FU ; Yiqi HE
Publication Type:Journal Article
Keywords: hyposemic ischemic encephalopathy, neonatal, monosialo gangliosides-1, Radix salviae miltiorrhizae
From: Chinese Journal of Rehabilitation Theory and Practice 2005;11(5):397-397
CountryChina
Language:Chinese
Abstract: ObjectiveTo observe the effect of monosialo gangliosides-1 (GM-1) and Radix salviae miltiorrhizae (RSM) on neonatal hyposemic ischemic encephalopathy (HIE).Methods62 cases of HIE were randomly divided into treatment group and control group, and both groups received conventional therapy. Injection of RSM and GM-1 were added into the treatment group in 7～10 days therapy. ResultsHigh curative effect, average curative effect and total curative effect in the treatment group of 31 cases were 80.6%, 16.1% and 96.8%, while that in control group of 31 cases were 32.3%, 51.6% and 83.9% respectively. There was significant difference in the high curative effect and total effect between the two groups (P<0.05). ConclusionThe treatment combined with RSM and GM-1 can enhance the curative effect on HIE without any side effect.