High sensitive Serum C-reaction protein in macrovascular disease with or without type 2 diabetes
- VernacularTitle:伴或不伴2型糖尿病大血管病变患者血清高灵敏度C-反应蛋白水平
- Author:
Hongwen LU
;
Yinhuan ZHANG
;
Lin LIU
;
Shouxiang SHEN
;
Xiangfeng MENG
- Publication Type:Journal Article
- Keywords:
type 2 diabetes, macrovascular disease, C-reaction protein
- From:
Chinese Journal of Rehabilitation Theory and Practice
2005;11(5):393-394
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo observe the changes of high sensitive serum C-reaction protein (hsCRP) in macrovascular disease with or without type 2 diabetes.MethodsThere were 3 groups population in our study:148 type 2 diabetic patients were divided into 2 subgroups:77 patients with macrovascular disease and 71 without macrovascular disease, 73 non-diabetic patients with macrovascular disease and 75 health controls. The concentration of serum hsCRP of all patients were determined by ELISA.ResultsThere was significant difference in concentration of serum hsCRP between type 2 diabetes with or without macrovascular disease groups, non-diabetes macrovascular disease group and control(P<0.01 or P<0.001). However, there was not significant difference between 2 diabetes groups and non- diabetic macrovascular disease group(P>0.05). There was no significant difference in hsCRP between type 2 diabetes with and without macrovascular disease (P>0.05).ConclusionThere may be a chronic inflammatory reaction in patients with type 2 diabetes or macrovascular disease. hsCRP might be a well forecasting factor of the occurrence and development of type 2 diabetes and atherosclerosis.
