The early diagnostic value of serum levels of myelin basic protein on degrees of spinal cord injury
- VernacularTitle:血清髓鞘碱性蛋白含量对脊髓损伤程度早期诊断的价值
- Author:
Ruisen ZHAN
;
Chaoyue ZHANG
;
Jianjun HUANG
- Publication Type:Journal Article
- Keywords:
degree of spinal cord injury, myelin basic protein, early diagnosis
- From:
Chinese Journal of Rehabilitation Theory and Practice
2005;11(4):271-272
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate the early diagnostic value of serum level of myelin basic protein (MBP) on spinal cord injury (SCI).Methods54 rabbits were divided randomly into slight, moderate and severe SCI groups, and SCI degrees of each group were judged by cortical somatosensory evoked potential, histopathologic examination and Tarlov′s score. ELISA was used to determine the serum levels of MBP before and after SCI.ResultsThe serum levels of MBP of rabbits in three groups were significantly different at 24th, 48th and 72nd hour after injured (P<0.05), but there were not differences at 7th day (P>0.05).ConclusionThe serum level of MBP can be used as a early diagnostic marker for SCI.
