Molluscum contagiosum-like lesions: A telltale sign of disseminated cryptococcosis
- Author:
Audi
1
;
Emmerson Gale S. Vista
2
,
3
;
Marie Claudine Francesca B. Perlas
1
;
Lunardi Bintanjoyo
1
;
Johannes F. Dayrit
2
Author Information
- Publication Type:Other Types
- MeSH: Cryptococcosis; Acquired Immunodeficiency Syndrome; HIV
- From: Journal of the Philippine Dermatological Society 2019;28(2):70-74
- CountryPhilippines
- Language:English
-
Abstract:
Introduction:Cryptococcosis is an opportunistic fungal infection caused by Cryptococcus neoformans. This systemic
fungal infection affects 6 to 13% of patients with acquired immunodeficiency syndrome (AIDS). Only 10% of patients
with this condition develop cutaneous manifestations.
Case Summary:A 20-year-old male, newly diagnosed case of HIV (Human Immunodeficiency Virus), presented with multiple skin-colored molluscum contagiosum-like umbilicated papules on the face, neck and both arms. Lesions increased in number rapidly and were associated with respiratory distress. Histopathologic examination revealed findings of opportunistic fungal infection suggestive of cryptococcosis. Serum Cryptococcal Antigen Latex Agglutination System (CALAS) test was also positive. Patient was then diagnosed as a case of cryptococcosis and was a candidate for intravenous amphotericin B. However, before the planned medication was given, the patient experienced severe respiratory distress and expired several hours later.
Conclusion:Molluscum-like skin lesions may be a telltale sign of a disseminated opportunistic fungal infection, including Cryptococcosis. Early diagnosis followed by prompt and aggresive treatment would improve outcome and survival of the patient. - Full text:jpds 31.pdf
