Effect of intravascular He-Ne laser irradiation on the abnormal lipid metabolism induced by clozapine
- VernacularTitle:氦氖激光血管内照射治疗氯氮平所致脂类代谢异常
- Author:
Yi-ping ZHU
;
Xue-min JIN
- Publication Type:Journal Article
- Keywords:
intravascular He-Ne laser irradiation (ILIB), schizophrenia, clozapine, lipid metabolism
- From:
Chinese Journal of Rehabilitation Theory and Practice
2004;10(4):205-206
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo observe the effect and side effect of intravascular He-Ne laser irradiation (ILIB) on the abnormal lipid metabolism induced by clozapine.Methods52 patients with schizophrenia (34 males, 18 females) took clozapine alone at a dosage of 200-350 mg/d. All patients were treated with ILIB every other day, 60 min once, ten times altogether. Before and after treatment, lipid metabolism, liver, kidney and blood coagulate functions of patients were tested.ResultsTC, TG, LDL-ch levels of patients decreased obviously after ILIB treatment (P<0.05), while HDL-ch level increased obviously (P<0.01). The liver, kidney and blood coagulate functions were as same as before treatment.ConclusionILIB has an extreme effect on the abnormal lipid metabolism induced by clozapine, and it is quite safe and has clinical practice value.
