Effect of glucocorticoid inhaled on bone metabolism, bone density and adrenal function in children with asthma
- VernacularTitle:糖皮质激素吸入疗法对小儿骨代谢和肾上腺功能的影响
- Author:
Huanzhi CHEN
;
Yizhen FENG
;
Jun WANG
;
Jiying WU
- Publication Type:Journal Article
- Keywords:
asthma, children, glucocorticoid
- From:
Chinese Journal of Rehabilitation Theory and Practice
2005;11(2):141-142
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo explore the effect of glucocorticoid inhaled on bone metabolism, bone density and adrenal function in children with asthma.Methods60 children were randomly divided into the treatment group and control group with 30 cases in each group, and having 30 pneumonia children as another control. Children of the treatment group were treated with budesonide (200~600 μg/d) inhaled, asthma cases in the control group without budesonide inhaled. Bone metabolism, bone density and adrenal function of children in three groups were compared.ResultsAfter 18 months treatment, there were no significantly differences of bone metabolism, bone density and adrenal function among children of three groups (P>0.05).ConclusionThe treatment of glucocorticoid inhaled is safe to asthma children.