The study of Yinaotongluo capsule preventing the microcirculation dysfunction in rats
- VernacularTitle:益脑通络胶囊预防微血管内血栓形成实验研究
- Author:
Meikui ZHANG
;
Ling YIN
;
Bin YAO
;
Yuying LIU
;
Xiumei ZHAO
;
Wei DU
;
Fengrong LIU
- Publication Type:Journal Article
- Keywords:
Yinaotongluo capsule, microcirculation, mesentery, rat
- From:
Chinese Journal of Rehabilitation Theory and Practice
2005;11(2):120-121
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo explore the effect of Yinaotongluo capsule on preventing the microcirculation dysfunction in rats.Methods40 SD rats were randomly divided into the thrombosis model group, three Yinaotongluo capsule groups (low, moderate and high dosages) and control group with 8 rats in each group. Photosensitizer was injected through vessel. Endothelium damage, cell adhesion and thrombosis were induced by photochemistry. The change of microcirculation was recorded and analyzed by microphotography technique.ResultsYinaotongluo capsule groups could prolong the time to thrombosis induced by photochemistry compared with control group (P<0.05). However, the area of thrombus to vessel significantly decreased in all Yinaotongluo capsule groups compared with control group (P<0.01). The effect of moderate dosage group of Yinaotongluo capsule was superior to Buchangnaoxintong group.ConclusionYinaotongluo capsule can improve the microcirculation of mesentery of rats, in part it can improve the systematic microcirculation of rats.
