The Effect of Short-term Treatment with Fennel on Bone Density in Postmenopausal Women: A Randomized Controlled Trial.
10.6118/jmm.2017.23.2.124
- Author:
Masumeh GHAZANFARPOUR
1
;
Elham AMINI
;
Talat KHADIVZADEH
;
Masoudeh BABAKHANIAN
;
Bahareh NOURI
;
Hassan RAKHSHANDEH
;
Maliheh AFIAT
Author Information
1. Department of Midwifery and Reproductive Health, Nursing and Midwifery School, Mashhad University of Medical Sciences, Mashhad, Iran.
- Publication Type:Randomized Controlled Trial ; Original Article
- Keywords:
Bone density;
Foeniculum;
Postmenopause
- MeSH:
Absorptiometry, Photon;
Bone Density*;
Female;
Femur;
Femur Neck;
Foeniculum*;
Follow-Up Studies;
Hip;
Humans;
Postmenopause;
Sample Size;
Spine
- From:Journal of Menopausal Medicine
2017;23(2):124-130
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVES: The goal of this study is to assess the effect of fennel on bone density. METHODS: This was a double-blind, randomized, placebo-controlled trial, which studied sixty eligible postmenopausal women, who were randomly assigned to fennel and placebo groups. Then, the dual energy X-ray absorptiometry was utilized to measure bone mineral density (BMD) and bone mineral content (BMC) of the spine, femoral neck, intertrochanter, and trochanter at the baseline and after three-month follow-up. RESULTS: The mean BMD and BMC at lumbar spine (P = 0.14, P = 0.504), total hip femoral (P = 0.427, P = 0.471), trochanter (P = 0.075, P = 0.07), intertrochanter, (P = 0.864, P = 0.932) and femoral neck (P = 0.439, P = 0.641) was not significantly different between the fennel and placebo groups. CONCLUSIONS: The results of this study did not approve the effect of fennel on bone density in post-menopausal women. However, to gain deeper insights, further studies with longer durations and larger sample sizes are recommended.