Effect of different doses of dihydroergotoxine on acute ischemic stroke
- VernacularTitle:不同剂量氢化麦角碱治疗急性缺血性脑卒中
- Author:
Hui ZHANG
;
Dong-sheng FAN
;
Xin-yu ZHANG
;
Liping WANG
;
Yan ZHANG
;
Ruping XIE
- Publication Type:Journal Article
- Keywords:
dihydroergotoxine, stroke, Danshen injection
- From:
Chinese Journal of Rehabilitation Theory and Practice
2004;10(3):179-180
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo observe the efficacy and safety of dihydroergotoxine in the treatment of acute ischemic stroke. Methods30 patients with acute ischemic stroke were randomly given dihydroergotoxine 0.6 mg(group 1), 1.5 mg (group 2) or Danshen injection 40 ml (group 3) respectively each day for 14 days,each for 10 cases. ResultsBefore and after treatment, the Scandinavian stroke scores of the three groups were increased(P<0.05). There was no significant difference(P>0.05) between the scores of group 1 and the group 3, but the scores of group 2 was higher than that of the group 3 and group 1(P<0.05). The common side-effect of both dihydroergotoxine groups were nausea, vomit, headache, palpitation and transient hypotention, which was more frequently apeared in group of 1.5 mg. ConclusionDihydroergotoxine and Danshen injection are all useful in the treatment of acute ischemic stroke. It is more efficient using higher dose of dihydroergotoxine. But as the dose going on, there will be more side-effect.
