Effect of Thrombus Aspiration and Tirofiban on Patients with Thrombotic Burden Lesion
- VernacularTitle:血栓抽吸联合替罗非班治疗血栓负荷病变疗效观察
- Author:
Quan YANG
;
Luyue GAI
;
Tingsh YANG
;
Yu WANG
;
Lian CHEN
;
Hongbin LIU
- Publication Type:Journal Article
- Keywords:
acute myocardial infarction, thrombotic burden lesion, thrombus aspiration device, tirofiban
- From:
Chinese Journal of Rehabilitation Theory and Practice
2007;13(12):1174-1175
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of both thrombus aspiration device Diver CE and tirofiban therapy on patients of acute myocardial infarction (AMI) with coronary thrombotic burden lesion.Methods 32 patients of AMI with thrombotic burden lesion confirmed by coronary angiography were divided into the aspiration catheter and tirofiban group (n=24) and standard percutaneous coronary intervention (PCI) group (n=8). The rate of major adverse cardiovascular events (MACE) in hospital, changes before and after the therapy of two groups were compared.Results MACE incidence in hospital in the patients of the both thrombus aspiration and tirofiban group was obviously lower than that of the standard PCI group ( P<0.05). The thrombolysis in myocadial infarction (TIMI) after therapy in the thrombus aspiration group improved superior to the standard PCI group. All of two groups had no fatal hemorrhagic complications.Conclusion Combination of thrombus aspiration and tirofiban is a safe and effective method to manage the thrombotic burden lesion in AMI patients.
