Effect analysis of PDCA cycle on prophylactic use of antibiotics in laparoscopic cholecystectomy during perioperative period
- VernacularTitle:PDCA循环对腹腔镜下胆囊切除术围手术期预防使用抗菌药物的影响效果分析
- Author:
Jingjing ZHANG
1
;
Fengling WANG
1
;
Xiangyun MENG
1
;
Dan SU
2
Author Information
1. Dept. of Pharmacy，Hefei Second People’s Hospital/the Affiliated Hefei Hospital of Anhui Medical University，Hefei 230011，China
2. Health Management Center，the First Affiliated Hospital of University of Science and Technology of China （Anhui Provincial Hospital），Hefei 230001，China
- Publication Type:Journal Article
- Keywords:
PDCA cycle;
laparoscopic cholecystectomy
- From:
China Pharmacy
2023;34(13):1632-1636
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To evaluate the effect of PDCA cycle on prophylactic use of antibiotics in laparoscopic cholecystectomy during perioperative period and to conduct pharmacoeconomic analysis. METHODS Using retrospective analysis method， 80 discharged patients of each group underwent laparoscopic cholecystectomy were randomly selected from Hefei Second People’s Hospital before PDCA cycle （from May to June 2019）， after the first round of PDCA cycle （from May to June 2020）， after the second round of PDCA cycle （from May to June 2021） according to real or basic reasons for irrational drug use. The rationality of prophylactic use of antibiotics for patients was evaluated. The general situation， antibiotic use， clinical efficacy and treatment cost of patients were compared before cycle and after the first and second rounds of PDCA cycle. Cost-effectiveness analysis method and sensitivity analysis method were adopted to evaluate pharmacoeconomic significance of PDCA cycle. RESULTS After two rounds of PDCA cycle， the irrational rate of antibiotics， cost ratio of antibiotics， the number of days of antibiotics use， DDDs， drug utilization index， the frequency of antibiotics use per capita， the total amount of antibiotics， the cost of antibiotics， the total amount of drugs， and the total cost of hospitalization all decreased significantly （P＜0.05）. The results of cost-effectiveness analysis indicated that the pharmacoeconomic effect was the best after two rounds of PDCA cycle； the results of sensitivity analysis were consistent with it， which confirmed the reliability of the research results. CONCLUSIONS PDCA CPA- cycle promotes the rational use of antibiotics of laparoscopic cholecystectomy during perioperative period， reduces the cost of antibiotics and relieves the economic burden of patients.
