Malignancy after Kidney Transplantation.
- Author:
Han RO
1
;
Sun Moon KIM
;
Ki Won KIM
;
Young Hwan HWANG
;
Jae Seok YANG
;
Kook Hwan OH
;
Yon Su KIM
;
Dong Wan CHAE
;
Curie AHN
;
Sang Joon KIM
;
Jong Won HA
Author Information
1. Department of Internal Medicine, Seoul National University College of Medicne, Korea.
- Publication Type:Original Article
- Keywords:
Kidney;
Transplantation;
Malignancy
- MeSH:
Allografts;
Anus Neoplasms;
Carcinoma, Renal Cell;
Cervix Uteri;
Colonic Neoplasms;
Conjunctiva;
Diagnosis;
Female;
Follow-Up Studies;
Humans;
Incidence;
Kidney Transplantation*;
Kidney*;
Liver Neoplasms;
Lymphoproliferative Disorders;
Pancreas;
Prevalence;
Sarcoma;
Sarcoma, Kaposi;
Skin Neoplasms;
Stomach Neoplasms;
Thyroid Neoplasms;
Tongue;
Transplantation;
Urinary Bladder Neoplasms
- From:The Journal of the Korean Society for Transplantation
2006;20(2):187-192
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Purpose: Development of malignancy is one of the key issues in the renal transplant recipients after long term follow up. Methods: We reviewed our renal transplant registry for the incidence of de novo malignancy after renal transplantation. Results: Among the 1006 renal transplant recipients from July 1969 until January 2006, 47 cases of de novo malignancy developed in 43 patients: stomach cancer (7 cases), Kaposi's sarcoma (6), post-transplantation lymphoproliferative disorder (PTLD, 7), primary liver cancer (4), thyroid cancer (3), skin cancer (4), colon cancer (3),), renal cell carcinoma (2), bladder cancer (2), anal cancer (2), sarcoma (3) and one malignancy case from conjunctiva, pancreas, uterine cervix, and tongue, respectively. Mean age at the time of diagnosis of cancer was 45.8+/-12.0 years (mean+/-standard deviation). The cancer diagnosis was made at 97.1+/-73.6 months after the renal transplantation. We have high prevalence of cancers with suspected viral etiology - i.e., Kaposi's sarcoma, PTLD, primary liver cancer and uterine cervix cancer. Conclusion: Careful surveillance of malignancy in renal allograft recipients is highly recommended.
