Treatment of Heteroptics after Cerebral Palsy with Transplantation of Human Neural Stem Cells into Cerebral Ventricle in Infants: 7 Case Report
- VernacularTitle:人神经干细胞移植治疗重度视觉障碍脑瘫患儿的临床观察
- Author:
Zuo LUAN
;
Suqing QU
;
Weipeng LIU
;
Xiaohong HU
;
Guocai YIN
;
Zhen JIN
;
Xiaojun GONG
- Publication Type:Journal Article
- Keywords:
neural stem cells, transplantation, visual disability, cerebral palsy
- From:
Chinese Journal of Rehabilitation Theory and Practice
2007;13(12):1103-1105
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical effect of human neural stem cells transplantation on severe visual disability infants after cerebral palsy. Methods Cells obtained from the forebrain of an 11-week-old abortive fetus were cultured and expanded for 15 days, then injected into cerebral ventricle of 7 patients. Results Their vision of 4 patients improved, as well as changes of flash visual evoked potential and functional magnetic resonance imaging in a few days after transplantation. Conclusion Neural stem cells transplantation may benefit in some CP children with severe visual disability.