Postoperative Analgesic Effects of Flurbiprofen Axetil Applied Preoperatively on Patients with Spinal Cord Injury
- VernacularTitle:术前应用氟比洛芬酯对脊髓损伤患者术后镇痛的效果
- Author:
Qiang WANG
;
Zengchun WANG
;
Haiquan LIU
;
Yi HONG
- Publication Type:Journal Article
- Keywords:
flurbiprofen axetil, preemptive analgesia, visual analogue scale(VAS), spinal cord injury, side effect
- From:
Chinese Journal of Rehabilitation Theory and Practice
2007;13(11):1019-1020
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the post-operative analgesic effect of flurbiprofen Axetil applied preoperatively on patients with spinal cord injury(SCI).Methods46 SCI patients undergoing spine surgery under general anesthesia were randomly divided into the flurbiprofen axetil group(group F)and control group(group C)with 23 cases in each group.Before cutting skin,flurbiprofen axetil(1 mg/kg)was injected intravenously in the group F,and normal saline(1 ml/kg)was infected intravenously in the group C.The scores of Visual Analogue Scale(VAS)for pain at postoperative 2,4,8,24,and 48 hours,and the incidence of side effects within 48 hours after operation were recorded.ResultsVAS scores at the time of 2,4,8,and 24 h after operation in the group F were significantly lower than that in the group C(P<0.05).But VAS scores of two groups at 48 h were not significantly different(P>0.05).The incidences of side effects of two groups were also not significantly different(P>0.05).ConclusionFlurbiprofen axetil applied preoperatively can release pain of SCI patients after spine surgery,and does not increase the incidence of side effects.
