Dynamic Analysis for Level of Plasma TXB2,6-keto-PGF1α and TXB2/6-keto-PGF1α of Patients with Acute Cerebral Infarction and Its Clinic Significance
- VernacularTitle:急性脑梗死患者血浆血栓素B2、6-酮-前列腺素F1α及其比值水平的动态变化与临床意义
- Author:
Zheng WANG
;
Yin-hua WANG
;
Feng GAO
;
Hongjun HAO
;
Weiping SUN
- Publication Type:Journal Article
- Keywords:
acute cerebral infarction, thromboxane B2(TXB2), 6-keto-prostaglandin F1α(6-keto-PGF1α), TXB2/6-keto-PGF1α, platelet
- From:
Chinese Journal of Rehabilitation Theory and Practice
2008;14(12):1156-1158
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the level of plasma thromboxane B2(TXB2),6-keto-prostaglandin F1α(6-keto-PGF1α) of patients with acute cerebral infarction,so as to know the changes of platelet function on acute cerebral vascular diseases.MethodsThe level of plasma TXB2,6-keto-PGF1α and TXB2/6-keto-PGF1α(T/6-K) of 205 patients with acute cerebral infarction were measured within 24 hours and on the 7th day and 14th day,and were compared with the normal controls(n=40).ResultsThe levels of plasma TXB2,6-keto-PGF1α of patients within 24 hours,on the 7th day and 14th day were significantly higher than those in the normal controls(P<0.01).The level of plasma TXB2 was the highest on the 7th day and decreased on 14th day.The level of plasma 6-keto-PGF1α was the highest on the 14th day.T/6-K was higher than those in the normal controls within 24 hours and on the 7th day;it was highest on the 7th day and decreased on 14th day to level of the normal controls(P>0.05).ConclusionThe determine on levels of plasma TXB2,6-keto-PGF1α has important significance for knowing the changes of platelet function on acute cerebral infarction.The balance between TXB2 and 6-keto-PGF1α is important in keeping the blood smoothly.
