Research of Plasma Endothelin-1,Nitrousoxide,Blood Gas,and Blood Viscosity in Patients with Chronic Pulmonary Disease
- VernacularTitle:慢性肺疾病患者血浆内皮素1、一氧化氮、血气与血液黏度关系的研究
- Author:
Jin-lan LI
;
Yi-qian ZHOU
;
Su-rong ZHANG
;
Xiaomei YUAN
;
Yuepeng GUO
;
Weixia YU
;
Yong QI
;
Zhiqiang ZHANG
- Publication Type:Journal Article
- Keywords:
chronic bronchitis, pulmonary emphysema, pulmonary heart disease, endothelin-1, nitrousoxide, blood gas analysis, blood viscosity
- From:
Chinese Journal of Rehabilitation Theory and Practice
2006;12(12):1100-1101
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the changes of plasma endothelin-1 (ET-1), nitrousoxide (NO), blood gas analysis, and blood rheology in patients with chronic bronchitis (CB), pulmonary emphysema (PE) and pulmonary heart disease (PHD) at different periods.Methods The plasma ET-1, NO, blood viscosity, hematocrit (Hct) and aggregation index (AI) of patients in groups of CB, PE and PHD, and the subjects of the control group were tested and compared. Blood gas analysis of subjects in four groups also performed and compared. Each group had 40 cases.Results In PE and PHD patients, the ET-1 level was higher, the indexes of blood gas analysis and blood rheology were abnormal. When PE developed into PHD, the ET-1 and PaCO2 tended to increase, PaO2 tended to decrease. When CB developed into PE and PHD, the blood viscosity, pressure volume and AI tended to increase, but NO tended to decrease.Conclusion When CB developed into PE or PHD, ET-1, PaCO2 tend to increase and NO, pH, PaO2 tend to decrease; increased red blood cells, blood viscosity and AI become severe.
