Clinical Significance of Oligoclonal Bands and IgG Index for Multiple Sclerosis
- VernacularTitle:寡克隆区带及IgG指数在多发性硬化中的临床意义
- Author:
Yuhui YIN
;
Hongjun HAO
;
Feng GAO
- Publication Type:Journal Article
- Keywords:
oligoclonal bands, IgG index, multiple sclerosis
- From:
Chinese Journal of Rehabilitation Theory and Practice
2007;13(9):888-890
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the positive rates of oligoclonal bands(OCB)and the IgG index in patients with multiple sclerosis(MS)and in other nervous system disorders(OND).Methods Cerebrospinal fluid(CSF)and serum were collected from 54 patients with MS,271 patients with OND including 62 patients with infections of central nervous system and 209 patients with non-infections.The OCB and IgG index of CSF and serum were detected.Results The positive rate of OCB was 35.2% in MS,8.9% in OND(P<0.05),in which 24.2% in infections of central nervous system(P>0.05),4.5% in non-infections of central nervous system.The positive rate of IgG index was 83.3% in MS,78.2% in OND(P>0.05).Conclusion OCB is helpful to diagnose MS if infection diseases have be excluded,while IgG index can be referenced.
