Quality of Life in Schizophrenics Treated with Aripiprazole or Clozapine
- VernacularTitle:阿立哌唑对精神分裂症患者生活质量的影响
- Author:
Peng HAN
;
Yu-hua ZHANG
;
Chuan-zhi ZHANG
;
Lan YU
;
Shaomin LI
;
Yongqiang ZHANG
- Publication Type:Journal Article
- Keywords:
aripiprazole, clozapine, schizophrenia, quality of life
- From:
Chinese Journal of Rehabilitation Theory and Practice
2006;12(11):995-996
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo campare the quality of life of schizophrenics treated with aripiprazole or clozapine.Methods90 cases with schizophrenia were randomly divided into aripiprazole group and clozapine group.After 6 mouths of treatment,all subjects were assessed with Positive and Negative Syndrome Scale(PANSS),WHO QOL-100 and Treatment Emergent Symptoms Scale(TESS).ResultsAripiprazole could significantly improve all aspects of quality of life except domination,and had a better result in physical,psychological,level of independence,solial relations,environment domain than clozapine did.Clozapine could only improve psyclological domain.There was no significant difference between the score of PANSS in two groups.However,aripiprazole had a better result in negative symptoms.ConclusionSchizophrenic outpatients treated with aripiprazole have a better quality of life than those with clozapine.
