Application of Trospium Chloride in Treatment of Overactive Bladder (review)
- VernacularTitle:曲司氯胺治疗逼尿肌过度活动症
- Author:
Qicong MO
;
Limin LIAO
;
Dong LI
- Publication Type:Journal Article
- Keywords:
overactive bladder, incontinence, spinal cord injury, maximal bladder capacity, trospium chloride, review
- From:
Chinese Journal of Rehabilitation Theory and Practice
2007;13(8):750-752
- CountryChina
- Language:Chinese
-
Abstract:
Trospium chloride is an anticholinergic agent with predominantly peripheral nonselective antimuscarinic activity and water solubility. It has potential therapeutic value in decreasing detrusor contracivity and tonity, so as to increase predominantly mean maximal bladder capacity and compliance. Multicenter studys showed that the tolerability and efficacy of trospium chloride was as same as oxybutynin and better than toterodine. Adverse events of trospium chloride is the same as other anticholinergic agents, however its specially constitutional feature so as not to have toxicity to central nervous system. Trospium chloride has potential therapeutic value in the neurourological rehabilitation.
