A Study of Retinal and Choroidal Vessel Changes in Chronic Alcoholics
10.3341/jkos.2023.64.6.507
- Author:
Inkee KIM,
1
;
Sung Won LEE
;
Hae Lim LEE
;
Ho RA
;
Jiwon BAEK
Author Information
1. Department of Ophthalmology, Bucheon St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Bucheon, Korea
- Publication Type:Original Article
- From:Journal of the Korean Ophthalmological Society
2023;64(6):507-513
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Purpose:To compare the retinal and choroidal vessels of chronic alcoholics with non-alcoholics.
Methods:This study included alcohol-associated liver disease (ALD) patients admitted between December 2020 and October 2021, along with age-matched controls. Retinal and choroidal vessel densities, measured using image binarization at the superficial capillary plexus (SCP), deep capillary plexus (DCP), choriocapillaris, and choroidal layers, were compared between ALD patients and controls. Correlations between clinical parameters and vessel densities in ALD patients were also analyzed.
Results:Vessel densities at SCP, DCP, choriocapillaris, and choroidal layers were not significantly different between controls and ALD patients (p = 0.496, 0.988, 0.909, and 0.317, respectively). Platelet time and international normalized ratio (INR) were positively correlated with SCP density in ALD patients (r = 0.393 and 0.393; p = 0.015 and 0.015, respectively).
Conclusions:ALD does not significantly affect vessel densities in the retina and choroid. The positive correlations of platelet time and INR with SCP may be related to vessel dilatation, but they require further investigation.
