A Case of de novo MPO-associated Central Nervous System Vasculitis Following Heterogeneous mRNA1273 COVID-19 Booster Vaccination
- Author:
Young Seok JEONG
1
;
Sung Jo BANG
;
Geun Yeong KIM
;
Jae Ho JEON
;
Gi Ryeong OH
;
Chong Hyuk CHUNG
;
Hyungjong PARK
Author Information
- Publication Type:Case Report
- From:Journal of the Korean Neurological Association 2023;41(2):145-148
- CountryRepublic of Korea
- Language:Korean
- Abstract: The coronavirus disease-19 (COVID-19) pandemic leaded to inevitable expeditious vaccine rollout without sufficient safety profile. Especially, severe acute respiratory syndrome coronavirus 2 infection has known to induce overreacted immune responses such as releasing of proteinase-3 and myeloperoxidase (MPO) by neutrophil. This overreacted immune response leads to the concern of the development of autoimmune diseases after COVID-19 vaccination. We report the case of de novo MPO-associated systemic vasculitis involving central nervous system following heterogeneous mRNA1273 COVID-19 booster vaccination.
