The Significance of Cervical Erosion with Benign Cellular Change on Papanicolaou Smear.
- Author:
Mee Jeong JOENG
1
;
Kum Ja PARK
;
Kook Young YOO
Author Information
1. Department of Obstetrics and Gynecology, Park Women's Clinic, Korea.
- Publication Type:Original Article
- Keywords:
Papanicolaou smear;
Benign cellular change;
Cervical erosion
- MeSH:
Biopsy;
Cervix Uteri;
Diagnosis;
Female;
Humans;
Papanicolaou Test*;
Papilloma;
Pathology;
Retrospective Studies;
Uterine Cervical Neoplasms
- From:Korean Journal of Obstetrics and Gynecology
1997;40(10):2241-2245
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The significance of cervical erosion with benign cellular change on Papanicolaou smear has not been evaluated. A retrospective review of 430 coloscopically directed punch biopsies performed over 15 months revealed 206 cases who had a benign cellular change on cytologic smear. Of these 206 smears, 48(23%) had clear cervix without erosion, 99(48%) had mild erosion on cervix, 41(20%) had moderate cervical erosion and 18(9%) had severe cervical erosion. The false negative rate that revealed more than mild dysplasia on histologic diagnosis was 2% in patients without cervical erosion, 3% in patients with mild cervical erosion, 5 % in patients with moderate cervical erosion, and 11% in patients with severe cervical er- osion. Koilocytotic change that suggested human papilloma virus infection was 17% in each group regardless cervical erosion. In conclusion, benign cellular change on Pap smears in patients with severe cervical erosion may be associated with significant cervical cancer pathology.