Significance of platelet parameters in the diagnosis of pediatric complicated acute appendicitis
- VernacularTitle:Хүүхдийн мухар олгойн цочмог үрэвслийн хүндэрсэн хэлбэрийн үед ялтсын нэмэлт үзүүлэлтийг тодорхойлохын ач холбогдол
- Author:
Ganbayar G
1
;
Baatarsuren B
1
,
2
;
Erdenetsetseg Ch
1
,
2
;
Bayartsetseg A
2
;
Odgerel Ts
1
,
3
Author Information
1. MJHMNUMS
2. Department of Surgery, MNUMS
3. Department of Hematology, MNUMS
- Publication Type:Journal Article
- Keywords:
children;
appendix;
mean platelet volume
- From:Innovation
2021;15(1):16-19
- CountryMongolia
- Language:Mongolian
-
Abstract:
Background:Acute appendicitis is an inflammatory disease and acommon cause of acute
abdominal pain. The application of the sophisticated automated hematology analyzer more
precisely define the morphology changes blood cells. According to this diagnose and treatment
control issues are solved by easy and not expensive way. Recent studies haveshown that there is a
negative correlation between platelet count (PC) and MPV and that theratio of these two values
may be more meaningful. The aim of our study was to investigate thediagnostic value of MPV and
the MPV/PC ratio in acute appendicitis.
Methods:The patients were divided into two groups based on their histopathological findings:
the uncomplicated and complicated appendicitis groups. Leukocyte count, PC, MPV and the
MPV/PC ratio were compared all groups.
Results:Total of 186 patients, including 119 men, were included in the study. The average age of
all patients was 10.21±1.22 years. There was statistically significant difference of some parameters
in peripheral blood between the uncomplicated and complicated appendicitis groups in terms
of all index. (p<0.001). Leukocyte count had a strong discriminatory property based on the area
under curve (AUC) 0.714, (p<0.001). MPV, PC and the MPV/PC ratio had weak discriminatory
power with AUC values <0.663. Using receiver operating characteristic (ROC) analysis, the
sensitivity and specificity of MPV were 81.56and 45.7%, respectively, and 63.78% and 71.06%,
respectively, for the MPV/PC ratio.
Conclusions:In our study, MPV and the MPV/PC ratio were useful in the diagnosis of acute
appendicitis.
- Full text:Innovation-2021-15(1);16-19.pdf
