Study of pathogen of oral candidias
- VernacularTitle:Амны мөөгөнцөр үүсгэгч мөөгний зүйлийг судалсан нь
- Author:
Namuunaa E
1
;
Suvdanchimeg A
1
;
Otgonjargal B
2
;
Tselmeg B
1
Author Information
1. Department of Pediatric and Preventive Dentistry, School of Dentistry, MNUMS
2. Department of Microbiology and Infection Prevention control, MNUMS
- Publication Type:Journal Article
- Keywords:
oral candidiasis;
fungal;
patients with full denture;
patients with radiotherapy;
antifungal drugs;
drugs
- From:Innovation
2021;15(1):12-15
- CountryMongolia
- Language:Mongolian
-
Abstract:
Background:Oral candidiasis, which is one of the most common diseases of the mucous
membrane, is carried in the mouth of about 17-75% of healthy population. And 51-74% of this
healthy population is asymptomatic. However, oral candidiasis is found in 50-65% of the individuals
with dentures, is found in 67% of elders over 75 years old and is found in 85% of the patients
with oral cancer. The most common causative organism is C.albicans with 43.7%, less commonly
C.glabrata and C.tropicalis. According to some researches, the occurrence of the oral candidiasis
has been increasing continuously for last 20-30 years, and has strong tendency to consistently
increase for the 21st century.
Methods:Total 50 patients were participated in this study, including; the patients with full denture
from Department of Prosthodontics of The Dental Center of Ulaanbaatar, and patients with
evident symptoms of candidiasis from Department of Neck and Head Surgery and Department
of Radiation Therapy of National Cancer Center of Mongolia. The study was carried out by
descriptive study type, based on the patients’ questionnaire survey, physical examination and
laboratory tests.
Results:The oral candidiasis causing pathogen Candida was found in 100% of following patients
including; the patients with full denture and the patients having head and neck radiation therapy.
For the patients with full denture, Candida albicans was the most commonly implicated organism
with 53%, Candida tropicalis 21% and Candida krusei 11%. For the patients with radiation therapy
for head and neck cancer, most common pathogen was Candida albicans with 64% and
Candida tropicalis with 7%.
Conclusions:Main causative pathogens for the patients with full denture are C.albicans (53%), С.tropicalis
(21%), and for the patients with radiotherapy for head and neck cancer is C. albicans (64%). 95%
of the participants who were diagnosed with oral candidiasis were resistant to Colistin and 100%
sensitive to Nystatin and Miconazole.
- Full text:Innovation-2021-15(1);12-15.pdf
