Screening and analysis of HCV among drug users in Dehong Prefecture， Yunnan Province from 2014 to 2021

Yanling LI; Yunqiu Zhang; Yuecheng Yang; Shijiang Yang; Renhai Tang; Jibao Wang; Jin Yang; Xing Duan; Yikui Wang; Runhua YE; Yingying Ding; Na HE; Song Duan

Return

Screening and analysis of HCV among drug users in Dehong Prefecture， Yunnan Province from 2014 to 2021

VernacularTitle:2014—2021年云南省德宏州吸毒人群丙型肝炎筛查分析
Author: Yanling LI ¹ ; Yunqiu ZHANG ² ; Yuecheng YANG ¹ ; Shijiang YANG ¹ ; Renhai TANG ¹ ; Jibao WANG ¹ ; Jin YANG ¹ ; Xing DUAN ¹ ; Yikui WANG ¹ ; Runhua YE ¹ ; Yingying DING ² ; Na HE ² ; Song DUAN ¹
Author Information

1. Dehong Prefecture Center for Disease Control and Prevention， Mangshi， Yunnan 678400， China
2. School of Public Health， Fudan University/Key Laboratory of Public Health Safety， Ministry of Education， Shanghai 200032，China
Publication Type:Journal Article
Keywords: hepatitis C virus; drug user; antibody positive; influencing factor
From: Shanghai Journal of Preventive Medicine 2023;35(3):229-234
CountryChina
Language:Chinese
Abstract: ObjectiveTo analyze the prevalence of HCV antibody positive and associated factors among drug users in Dehong Prefecture， Yunnan， and to provide scientific evidence for HCV prevention. MethodsQuestionnaire surveys and serological testing were conducted among 400 drug users continuously selected from four national AIDS sentinel surveillance in Dehong Prefecture between January and July during 2014‒2021. Results11 683 drug users were included. The prevalence of HCV antibody positive was 20.2% overall， and 14.9%， 20.1%， 22.4%， 19.8%， 22.5%， 20.6%， 24.5%， 19.0% from 2014 to 2021， respectively （trend Z=-3.78， P<0.001）. Multivariable analysis indicated the following were independently associated with HCV antibody positive： that older age （OR=1.02， 95%CI： 1.02‒1.03）， male （OR=1.70， 95%CI： 1.19‒2.42）， unmarried （OR=1.64， 95%CI： 1.44‒1.87）， divorced or widowed （OR=1.73， 95%CI： 1.48‒2.02）， Jingpo ethnicity （OR=1.39， 95%CI： 1.19‒1.63）， injection drug use （OR=15.46， 95%CI： 13.13‒18.12）， and HIV infection（OR=4.96， 95%CI：4.12‒5.99）. ConclusionThe prevalence of HCV antibody positive among drug users in Dehong Prefecture is high and increases with some fluctuations during 2014 to 2021， which highlights the need to develop interventions targeting this population.