Research progress on role of angiopoietin-like 4 in tumor progression
10.13200/j.cnki.cjb.003852
- VernacularTitle:血管生成素样蛋白4在肿瘤进程中作用的研究进展
- Author:
XU Jinge
- Publication Type:Journal Article
- Keywords:
Angiopoietin-like 4(ANGPTL4);
Tumor growth;
Tumor metastasis;
Tumor angiogenesis
- From:
Chinese Journal of Biologicals
2023;36(3):373-
- CountryChina
- Language:Chinese
-
Abstract:
Angiopoietin-like 4(ANGPTL4)is one of the angiopoietin family members and plays a regulatory role in lipid metabolism,glucose homeostasis,inflammatory signal transduction,angiogenesis and vascular permeability.Inflammatory reaction in tumor microenvironment regulates tumor progression,and tumor angiogenesis plays a vital role in tumor growth and metastasis,so ANGPTL4 is closely related to tumor occurrence and development.Many studies have shown that ANGPTL4 plays an important regulatory role in tumor growth,anoikis resistance,tumor angiogenesis and tumor metastasis.This paper reviews the role of ANGPTL4 in tumor progression.
