Analysis of Helicobacter pylori infection and its correlation with serum bilirubin in railway drivers
- Author:
JIAO Lin lin ZHANG Lei LI Yu zheng JIN Chao mei ZHOU Rong ZHANG Si yu TIAN Mei ZHOU Fang
- Publication Type:Journal Article
- Keywords:
Helicobacter pylori； ； ； ； ； ； Infection Serum Bilirubin Correlation Railway Driver
- From:
China Occupational Medicine
2022;49(05):577-
- CountryChina
- Language:Chinese
-
Abstract:
Objective Helicobacter pylori（ ），
To investigate the infection status of HP and analyze the correlation between HP
Methods
infection and serum bilirubin in railway drivers. A total of 2 731 railway drivers in Zhengzhou locomotive depot were
-
selected as study subjects using judgment sampling method. Carbon 13 urea breath test was used to evaluate the HP infection
，
status. The metabolic indexes of HP positive group and HP negative group were compared and the relationship between HP
Results （ ） ，
infection and serum bilirubin was analyzed. The HP infection rate was 42.3% 1 156/2 731 . The older the age the
， （ ）， （ P ）
longer the work years and the higher the body mass index BMI the higher the HP infection rate all <0.01 . The infection
（P ）
rate of HP in married people was higher than that in unmarried people <0.01 . The HP infection rate of smokers was higher
- （P ） - ，
than that of non smokers <0.01 . Compared with the HP negative group fasting blood glucose and serum levels of total
， （ - ）， （ ） -
cholesterol low density lipoprotein cholesterol LDL C triglyceride and homocysteine Hcy were increased in the HP
（ P ） （ - ）， ，
positive group all <0.05 . The serum levels of high density lipoprotein cholesterol HDL C total bilirubin direct bilirubin
（ ） - （ P ）
DBIL and indirect bilirubin were lower than those in HP negative group all <0.05 . Logistic regression analysis showed that
（ P ）
HP infection was associated with low serum total bilirubin and low DBIL all <0.01 after adjusting for the confounding effects
， ， ， ， ， ， ， - ， - ，
of age work years marital status smoking history fasting blood glucose total cholesterol triacylglycerol LDL C HDL C
Conclusion ， ， ，
and Hcy. The age work length BMI smoking and marital status are the influencing factors of HP infection in
railway drivers. HP infection is associated with low levels of total bilirubin and DBIL.
