Effects of mineral-rich salt intake on the serum and blood pressure of Dahl salt-sensitive rats.
- Author:
Yong Xie JIN
1
;
Haeng Ryan KIM
;
Jin Hyo KIM
;
Kun Young PARK
;
So Young KIM
Author Information
1. Division of Functional Food & Nutrition, National Academy of Agricultural Sciences, National Academy of Agricultural Sciences, Rural Development Administration (RDA), Suwon 441-853, Korea. foodksy@korea.kr
- Publication Type:Original Article
- Keywords:
blood pressure;
Dahl rat;
mineral-rich salt;
triglyceride;
ACE
- MeSH:
Blood Pressure*;
Cholesterol;
Human Body;
Humans;
Lipid Metabolism;
Male;
Rats, Inbred Dahl*;
Triglycerides
- From:Journal of Biomedical Research
2013;14(4):212-219
- CountryRepublic of Korea
- Language:English
-
Abstract:
This study was conducted in order to determine the functionality of mineral-rich salt with lower NaCl and higher mineral contents on blood pressure and lipid metabolism in Dahl salt-sensitive rats. A 1% salt solution was administered to five-week-old male Dahl rats- one normal and three salt groups (Purified salt, sun-dried salt, and bamboo salt) for 15 weeks. On the basis of the salt production process, the sun-dried group was classified into two subgroups: SS1 (2-year) and SS2 (>5-year) depending on the storage period of the mineral-rich salt. The relationships between salt intake and changes in blood pressure, serum lipids, and serum mineral concentrations were then examined. The results showed that intake of SS2, which is stored for five years, and BS (bamboo salt) resulted in continuous delay of the increase in blood pressure and inhibited angiotensin-converting enzyme (ACE) activity. In addition, a significant decrease in the triglyceride level in serum lipids of approximately 30% was observed in the SS2 group compared to the PS (purified salt) group. However, all salt intake groups showed an increase in total cholesterol levels compared to the normal group. The results demonstrate that intake of mineral-rich salt is beneficial for the human body and results in reduced blood pressure and triglyceride levels in serum lipids, however, conduct of more research will be needed in order to explore other functions.
