Technological and standardization study of “tomuun ” 100 ml syrup medicine
- VernacularTitle:“Томуун” 100 мл сироп эмийн технологи, стандартчилалын судалгаа
- Author:
Battulga G
1
;
Oyunbileg S
;
Khurelbaatar L
Author Information
1. Drug Research Institute, Monos group
- Publication Type:Journal Article
- Keywords:
chlorphenamin maleat;
paracetamol;
ascorbic acid;
tomuun 100.0 ml syrup;
- From:Mongolian Medical Sciences
2012;162(4):98-102
- CountryMongolia
- Language:Mongolian
-
Abstract:
BackgroundOn the basis of criteria and indicators of national and international pharmacopoeia pharmacopoeia medicament in syrup determined the composition. On formulations of sweet juice syrup medicine Tomuun received 100 ml. Improved composition drazhzhe “Tomuun 5g,” which made us and added substance has antihistaminic action - chlorphenamine maleate. This additional structure of the flu as well as infectious and inflammatory diseases have a symptomatic effect, that is, reduces tearing, nasal swelling of the nasal mucosa. As the research result shows, Tomuun syrup 100 ml contains ascorbic acid 10.2 ml / mg, paracetamol 2.5 mg / ml, chlorphenamine maleate 0.41 mg / ml.GoalsThe aim of this study was to develop a new generic medicine’s technology and standardization producers. Materials and MethodsSeveral methods have been used for technological producers and chemical analysis in this study. “Tomuun 100 ml” syrup medicine prepared for general cooking techniques syrup medicine. Indicators for Standardization syrup medicine “Tomuun 100 ml” developed on the basic documents of national and international pharmacopoeia. The thin-layer chromatography and HPLC methods used for determining the content of paracetamol and ascorbic acid.ResultsWe have researched the indication syrup medicine for production technology and projected the standardization producers on syrup medicine according to national and international pharmacopoeias.ConclusionAs results from this study shows that “Tomuun” syrup medicine is suitable for several above mentioned criteria and used technological and chemical methods such as HPLC and thin layer chromatography are acceptable for generic medicine’s standard documentation for this medicine.
