Primary rectal mature teratoma: a case report.
- Author:
Yong Moon LEE
1
;
Joung Ho HAN
;
Ho Chang LEE
Author Information
1. Department of Pathology, College of Medicine, Chungbuk National University, Cheongju 361-763, Korea. fgump0@chungbuk.ac.kr
- Publication Type:Case Report
- Keywords:
dermoid cyst;
meiosis;
polyps;
rectum;
teratoma
- MeSH:
Ambulatory Care Facilities;
Blood Vessels;
Dermoid Cyst;
Eccrine Glands;
Ectoderm;
Endoderm;
Epidermis;
Female;
Germ Cells;
Hair Follicle;
Humans;
Incidence;
Lymphocytes;
Male;
Mastectomy, Segmental;
Meiosis;
Mesoderm;
Middle Aged;
Mucins;
Muscle, Smooth;
Neoplasm Metastasis;
Ovary;
Polyps;
Rectum;
Recurrence;
Respiratory Mucosa;
Sebaceous Glands;
Sex Chromosomes;
Surgical Procedures, Minimally Invasive;
Sweat Glands;
Teratoma*;
Thyroid Gland
- From:Journal of Biomedical Research
2013;14(4):249-252
- CountryRepublic of Korea
- Language:English
-
Abstract:
This report describes a rare case of primary rectal mature teratoma in a 56-year-old woman. She was referred to the outpatient clinic with a large pedunculated rectal mass, which was found during a regular health check-up. Polypectomy was performed and microscopic findings showed various structures derived from all three germ cell layers. Epidermis, hair follicles, sebaceous glands, eccrine glands, and apocrine sweat glands, with some scattered melanophages and lymphocytes were present as ectodermal derivatives. Smooth muscle fibers, blood vessels, and fibrous and adipose tissues were found as mesodermal derivatives. In addition, thyroid follicles, mucinous glands, and bronchial respiratory epithelium with peribronchial glands were detected as endodermal derivatives. She is healthy and has shown no evidence of recurrence or distant metastasis for 25 months post-surgical resection. Primary rectal teratomas are generally benign and primarily affect women. Therefore, minimally invasive surgical procedures, such as endoscopic polypectomy for a pedunculated polyp and segmentectomy for a larger mass, are satisfactory in most cases. Induction of primary rectal teratomas has been suggested to occur mainly by errors in a single germ cell after the end of meiosis I; in addition, it has also been suggested that the difference in gender incidence may be associated with differences in sex chromosomes between males and females rather than with anatomical proximity between ovary and rectum.
